Lucas Decuypere

CEO

Allegro (Antwerp, Belgium) is changing the trajectory of chronic joint disease, introducing the first disease-modifying injectable, combined with real-time diagnostics, and precision delivery to redefine how osteoarthritis and related conditions are treated.

Therapeutic: Orthopedics-Spine; Osteo Arthritis

Michael Mrochen

Co-Founder

Presbyopia affects over 2 billion people and remains insufficiently addressed. We have introduced a tissue-based corneal solution, already commercially launched in Europe and Canada with growing surgeon adoption and repeat sales. In parallel, we secured FDA IDE approval for our U.S. feasibility study, positioning us for structured expansion into North America. This is a company moving from validation to scale—commercial revenues today, regulatory milestones ahead, and a clear pathway to strategic value creation.

Therapeutic: Biomaterials; Tissue technology

Isabel Schellinger

CEO

Angiolutions (Hannover, Lower Saxony, Germany) is a medical technology company pioneering a new treatment for abdominal aortic aneurysms, a major vascular disease affecting roughly 1 in 20 individuals aged 60 years and older. Angiolutions’ A3-Shield® System is a first-of-its-kind aortic implant designed to stop the disease by addressing its root cause through local modulation of aortic pulse waves. The company is currently conducting its first-in-human clinical trial and closing its Series A financing round. For more information, visit angiolutions.com or follow Angiolutions on LinkedIn.

Therapeutic: Cardiovascular

David Neale

CEO

Cardiac Ablation. Coherent Sine Burst Electroporation, the next Generation Pulsed Field Ablation fro treatment of Atrial Fibrillation and other arrhythmias.

Therapeutic: Cardiovascular

Mathieu Horras

CEO

Aspivix (Lausanne, Switzerland) is a Swiss MedTech company developing innovative solutions to modernize gynecology and improve women’s experience during office-based procedures. Its first product, carevix®, is a single-use, vacuum-based cervical stabilization device designed to replace the traditional cervical tenaculum, a traumatic instrument commonly used during IUD insertion and other intrauterine procedures. By stabilizing the cervix through gentle suction rather than piercing tissue, carevix® significantly reduces pain, bleeding, and procedural trauma. Aspivix aims to set a new standard of care in gynecology by making procedures safer, gentler, and more acceptable for women worldwide.

Therapeutic: Women’s Health; Gynecology; Contraception; Fertility

ATRO Medical (Nijmegen, the Netherlands) develops Artimis® - the first nature-mimicking artificial meniscus aiming to relief pain for all those patients suffering from persistent knee pain after (partial) meniscectomy. The Artimis® Meniscus Prosthesis is under clinical evaluation in multiple European clinical studies. 

Eric Meeder

CEO

SyCap from Avalanche Medical (Maastricht, Netherlands) is a groundbreaking solution for middle-aged patients (35–65 years old) suffering from focal cartilage defects. It bridges the treatment gap between cartilage repair and total knee replacement (TKR), offering a joint preservation approach. It improves quality of life by addressing debilitating symptoms of cartilage defects. The implant is designed to postpone the need for total knee replacement and to delay the onset of Osteoarthritis. We have a 1,4B market opportunity and potential line expansion.

Therapeutic: Orthopedics-Spine; Focal Cartilage defect

Sarah van Hellenberg Hubar-Fisher

CEO

Bioretec’s (Finland) breakthrough technologies — RemeOs™, the first osteopromotive absorbable metal implant, and Activa, the first self-reinforced polymer implant — define a new standard of care: two absorbable technologies, one goal — healing beyond absorption.

Therapeutic: Orthopedics-Spine

Chloe Brown

CEO

Ceroflo (Galway, Ireland) is a clinical-stage neurovascular company developing the SubMax Stent to treat intracranial atherosclerotic disease and prevent ischemic strokes. The company targets the large population of patients who suffer from narrowed brain arteries and remain at high risk of stroke despite standard medication. The SubMax Stent utilizes a proprietary structure designed to gently restore blood flow through delicate and tortuous intracranial vessels. This technology provides a stable scaffolding that stabilizes plaque while conforming to the natural anatomy of the cerebral vasculature. This approach differs from first-generation stents which were often associated with high rates of vessel trauma and procedural complications. By focusing on atraumatic dilation, the system aims to provide a more predictable and safer interventional option than existing mechanical or pharmaceutical treatments.

Therapeutic: Neurovascular; Stroke; Neurology; Endovascular

Frank Desiere

CEO

CorTec (Freiburg, Germany) provides the Brain Interchange (BIC), a fully implantable, wireless, 32-channel closed-loop brain-computer interface capable of simultaneous neural sensing and electrical stimulation. The system utilises flexible ECoG surface electrodes to interact with neural networks at the cortical level, avoiding the tissue damage associated with penetrating microelectrodes. It is currently in human clinical trials for stroke rehabilitation, addressing a multi-billion dollar therapeutic market that includes neurorehabilitation, depression, and other psychiatric disorders.

Therapeutic: Neuromodulation-Neurostimulation; Brain-Computer Interfaces

Patrick Killoran

Managing Director/CSO

Founded at the University of Cambridge’s Darwin Building, Depletura Ltd (Ely, Cambridgeshire, UK) is advancing bleeding management through novel collagen-based haemostatic technology. Integrating academic research with frontline clinical insight, and backed by a leading professor of trauma surgery, the company develops scalable, next-generation solutions for emergency, surgical, and trauma care. The Clotta™ (human) and ClottaVet™ (veterinary) platform delivers rapid, reliable bleed control designed for real-world clinical performance and commercial deployment.

Therapeutic: Bleed control, trauma medicine, surgery

Kei Mueller

CEO & Co-founder

Digital Twins Guiding Pulmonary Care. From Munich/Bavaria, Germany.

Therapeutic: Artificial Intelligence; Respiratory, Health Tech

Maurits Huigen

CEO

Gilbert (Eindhoven, The Netherlands) is a Dutch MedTech company revolutionizing inhaled therapies with precision delivery of advanced therapies, with its next-gen Smart Precision Inhaler device. Gilbert's breakthrough scalable delivery platform offers the precision and adaptability modern inhaled therapies require - and the simplicity patients demand; a launchpad for next-gen therapies.

Therapeutic: Respiratory; Precision Medicine

Martin Stauber

CEO & Founder

GratXray (Schlieren, Zurich, Switzerland) is an innovative medical technology company dedicated to transforming diagnostic imaging. As a spin-off from Paul Scherrer Institute and ETH Zurich, we combine world-class research with practical innovation to address real clinical needs. Our first product, senoa, revolutionizes breast cancer diagnosis with pain-free, high-precision 3D imaging. By eliminating the compression required in traditional mammography and prioritizing patient comfort, we're making life-saving breast imaging more accessible, especially for women who have avoided screening due to discomfort or fear.

Therapeutic: Imaging; Breast cancer imaging

Arash Dodge

CEO

Haermonics (Eindhoven the Netherlands) is a clinical stage MedTech company. Our mission is to make post-operative cardiac surgery care safer, while reducing workload of ICU personnel, and reducing healthcare costs. Our patented continuous postoperative pericardial flushing therapy has shown both reduction of patient blood loss and re-operation rates in RCT settings. Our short-term focus is to bring our first product to market in 2026. Having FDA breakthrough designation, we seek funding for FDA/post-market studies, and product redesign for scale.

Therapeutic: Cardiovascular

Sophie Brac de la Perrière

CEO & co-founder

Healshape (Lyon, France) is a regenerative medicine company aiming company aiming to empower patients to regenerate themselves. Our first product is a 100% natural and resorbable bioprosthesis for women who have undergone a mastectomy following breast cancer. This soft, biosourced, 3D printed scaffold promotes natural tissue regeneration in the patient before being absorbed.

Therapeutic: Oncology; Women's Health

Lukas Lindenroth

CEO

Helico Technologies (London, United Kingdom) leverages soft robotics and AI to pioneer precision treatment delivery deep inside the human body. Starting with otology, our platform, Soro-tymp, is a minimally invasive steerable balloon otoendoscope designed to augment clinicians in delivering next-generation care to the middle and inner ear.

Therapeutic: ENT; Otology; Drug Delivery

Thomas Bancel

CEO

Endobronchial ablation with real-time control.

Therapeutic: Minimally invasive surgery; Interventional / Respiratory

David Israeli

CEO

The Elevate™ percutaneous Left Ventricular Assist Device (pLVAD) from Magenta Medical (USA) is a self-expanding percutaneous heart pump, intended to provide temporary mechanical circulatory support for the left ventricle (LV) during high-risk percutaneous coronary interventions (HR-PCI) and in patients admitted with cardiogenic shock (CS).

The Elevate™ Pump is delivered sheathed into the LV through any number of commercially available 10 Fr femoral introducer sheaths, fully over-the-wire (0.018”). Once in the LV, the self-expanding pump is un-sheathed, expanding from 9 Fr to 30 Fr.

The Elevate™ Pump can deliver >5.4 L/min of mean flow from the LV to the ascending aorta (peak flow exceeds 8 L/min).

Therapeutic: Temporary mechanical circulatory support for high-risk percutaneous coronary interventions and cardiogenic shock

Keith Carlton

Executive Chairman

Newronika (Milan, Italy) is a venture-backed, clinical-stage neuromodulation company developing best-in-class adaptive deep brain stimulation (aDBS) systems that personalize therapy in real time to deliver more precise treatment for those suffering from neurological disorders starting with Parkinson’s disease. Newronika's flagship product is AlphaDBS, a closed-loop aDBS system designed to sense and interpret bioelectrical neuronal activity (e.g. local field potentials) deep in the brain where stimulation is delivered and adapts the output stimulation moment-by-moment to provide superior, patient-specific therapy with fewer side effects than conventional DBS therapy.

Therapeutic: Neuromodulation-Neurostimulation; Biomarkers

Jonas Steinhauser-Meerz

Designated CEO/Managing Director

NGScopes (Dresden, Saxony, Germany) develops lightweight, through-the-scope robotic instruments for endoscopy that integrate seamlessly into existing workflows. Our technology enables millimeter-precise control of endoscopic tools independently of the endoscope, expanding therapeutic capabilities and enabling faster, safer procedures.

Therapeutic: Gastroenterology; Robotics

Marie-Louise Little

CEO

O2matic (Herlev, Denmark) delivers automated oxygen therapy that replaces manual, error‑prone titration with precise, real‑time adjustment based on continuous SpO₂ monitoring. The platform improves outcomes, reduces severe hypoxemia, lightens staff workload, and supports hospital, home, and pre‑hospital use. Entering a high‑growth phase, O2matic is preparing FDA De Novo submission, expanding in Europe, and raising a €5M Series A2 to drive U.S. launch, regulatory milestones, and OEM integrations. With strong clinical evidence and partnerships, it is poised to set a new global standard in oxygen therapy.

Therapeutic: Respiratory

Corentin Gondrand

CEO

For transplant patients, waiting days for blood test results can mean the difference between timely treatment and dangerous complications. Under the direction of Co-Founder and CEO Corentin Gondrand, QuantiLight (Heidelberg, Baden-Wurttemberg, Germany) is eliminating that wait, delivering lab-grade results in just 15 minutes, right at the point of care. Fueled by bioluminescent sensor technology from the Max Planck Institute for Medical Research, the Heidelberg-based startup is addressing delays in therapeutic drug monitoring (TDM) that affect millions of patients worldwide. Backed by clinical proof-of-concept and advancing toward CE-IVD and FDA submissions, QuantiLight is on track to transform diagnostic workflows for transplant patients and beyond.

Therapeutic Category: Diagnostics

Ciarán Duffy

Commercial Lead

SmartCare (Head Office: 3 The Forum, Icknield Way Industrial Estate, Tring, Herts. UK HP23 4JY) is developing the world's first lab standard HbA1c fingerstick test and an innovative diabetes management app, designed alongside patients with the help of The Listening Lab (Diabetes UK).

The SmartCare System will revolutionise care, enabling people with type-2 diabetes to manage their condition much more effectively and live healthier lives.

It addresses the needs of 640 million people worldwide and a global market worth $62 billion by 2030; it will play an essential role in the fight against the global diabetes epidemic.

Ciarán Duffy

Commercial Lead

The SMARTSHAPE device and platform from (Galway, Ireland) provides continuous blood pressure monitoring that transforms blood pressure from occasional snapshots into high-fidelity, clinically useful trends for diagnosis and therapy optimization.

With the  potential to establish a new standard of care, SMARTSHAPE will enable personalized care for patients with the highest cardiovascular risk.

Therapeutic: Cardiovascular Disease Management (Hypertension Management)

Kieran Murphy

Chairman, Interim CEO, Founder

SpinaFX (Toronto, ON, Canada) is a medical device company that has developed a minimally invasive, image-guided therapy for lumbar disc herniation, addressing a critical gap between conservative care and surgery. Our patented technology, Triojection®, uses a standard spinal needle to deliver a metered oxygen-ozone gas mixture into the affected disc, reducing disc volume and thereby relieving nerve root compression to provide lasting pain relief.

Therapeutic: Orthopedic/Spine

Andrew Grace

CEO

TCEB (Cambridge, United Kingdom) provides the means to obtain frozen tissue/cells enabling disease characterisation that in turn will guide precision therapy. In this journey we introduce a differentiated, IP-protected biopsy platform that enables clinical access with strikingly reduced complications termed Targeted Cryo-Enabled Biopsy (TCEB). Initial applications will be in cardiology but rapidly extend to oncology directly addressing major unmet needs thereby bridging gaps to the laboratory bench.

Therapeutic: Oncology; Cardiovascular