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4C Medical Technologies (Brooklyn Park, MN) is focused on minimally invasive therapies for structural heart disease, specifically mitral valve regurgitation.

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AiM Medical Robotics (Fort Lauderdale, FL) is developing an MRI compatible surgical robotic system for advanced neurosurgical procedures. MRI compatibility allows the robotic system to provide real time image guidance and automated precision movements. Our robotic system will drive better outcomes in a less invasive and more timely fashion than existing operating systems.


Aplos Medical (Eden Prairie, MN) is developing the Ω-Cuff, a simple, easy and safe laparoscopic implant for 40% of GERD patients currently on PPIs. The small Ω-shaped device is designed to prevent excessive acid from entering the esophagus while minimizing dysphagia and side effects common to other GERD treatments. It is FDA approved to enter into a clinical trial.

Articulate Labs (Dallas, TX) develops wearable medical devices that help make physical rehabilitation faster and more convenient. Articulate Labs develops wearable medical devices that accelerate joint rehabilitation by augmenting a patient’s everyday muscle usage with electrical muscle stimulation. By leveraging everyday activity to actively combat muscle atrophy and inhibition related to chronic conditions or surgery, our devices make physical rehabilitation more accessible, convenient, and effective. Their first device, KneeStim, will assist with quadriceps re-strengthening and re-education for those recovering from knee surgery or coping with chronic knee conditions.


Aspisafe Solutions (Brooklyn, NY) is a Medical Device startup in the feeding tube space. It aims to bring 3 products to market. Our flagship product is a nasogastric tube that has a proprietary communicating balloon technology to prevent reflux and thus would be able to prevent pneumonias that are linked to stomach aspiration. We believe by abolishing reflux in certain patient populations, billions of dollars worth of complications will be saved, and patient outcomes will improve.


Augustine Surgical

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AusculTech Dx (Dayton, MD) technology is a digital auscultation platform that enables easy recording and cloud-based storage and sharing of heart sounds using a mobile app. Embedded in the app are clinically validated machine learning algorithms that help identify innocent Still’s murmur with cardiologist-level accuracy at the point of recording.


BioAesthetics (Research Triangle Park, NC) is transforming lives through advancements in biomaterials. The company has developed NACgraft - an acellular biologic graft for regeneration of the nipple-areolar complex (NAC) for breast cancer-related mastectomy patients.

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BioDirection, Inc. (Southborough, MA) is a privately-held medical device company developing novel and rapid point-of care products for the objective management of concussion and other traumatic brain injuries (TBI). The Tbit® System is an immunoassay based on silicon nanowire (SiNW) technology to quantitatively measure (Protein Biomarkers) in capillary whole blood from a fingerstick collected by a healthcare professional. The Tbit assay is performed using the Tbit Analyzer in point-of-care settings. The Tbit System is a valuable adjunctive tool for determining those suspected Traumatic Brian Injury (TBI) patients who are most suitable for further CT evaluation for the diagnosis of TBI.


Clarix Imaging (Chicago, IL) is developing the volumetric specimen imager (VSI), an intra-operative 3D imaging-based solution for accurate, workflow-friendly margin assessment, thereby lowering the 25% re-operation rate of breast conserving surgery. Having raised $4.7 million non-dilutive and private seed investments for product development and initial regulatory clearances, Clarix Imaging is seeking another round of financing for manufacturing and commercial launch in 2020.


COVR Medical LLC (Rochester, MN) markets a line of proprietary garments designed to provide patient privacy in medical procedures while still allowing for procedural access to the hip/groin area by medical professionals.

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Embody LLC (Norfold, VA) is a medical device company developing collagen-based implants for the treatment of tendon and ligament injuries. With $12 million in funding from DARPA, Embody will launch our Tapestry Achilles implant in 2019 following FDA 510(k) clearance. In 2020, we will launch the first collagen internal brace and a Tapestry Rotator Cuff Implant. We have over $6 million in guaranteed, non-dilutive funding going forward, so our investors are funding commercial launch and revenue generation.

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gel-e (College Park, MD) is a clinical-stage medical device company developing versatile hemostatic products for surgical, medical, and consumer applications. gel-e combines the use of safe, inert ingredients with proprietary chemistry across a broad spectrum of clinical applications. The company has raised over $9M through private equity and grant funding for the commercial launchpad for multiple gel-e products. gel-e has been featured on the BBC’s “Brave New World” with Stephen Hawking based on 3 FDA Clearances, 7 issued patents and 7 peer-reviewed publications.

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Imago Systems (Lansdowne, VA) has developed a platform software solution, which utilizes the latest in machine learning to re-visualize existing medical/mammography images. Using the existing workflow, Imago ICE will provide a series of visualizations enabling unprecedented levels of detail. It reveals recognizable patterns, enabling clinicians to see lesions that would have been missed (false negatives) and bypass objects they might have mistaken for cancer (false positives). Clinicians will be better equipped to make timely and accurate recommendations for optimal diagnosis and treatment.

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InterShunt (St. Louis, MO) is developing a minimally-invasive surgical catheter for the treatment of heart failure. The catheter creates a shunt in the interatrial septum without leaving behind an implant. This allows for a reduction of pressure in the left atrium and a reduction of symptoms. HF is the single largest unmet medical need with no effective therapies, leaving doctors and patients desperate. InterShunt is led by seasoned medical device executives, clinicians and engineers who have built a program to ensure we are the leader in interatrial shunting.

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Lineus Medical (Fayetteville, AR) Patients in the hospital dislodge their IVs 11% of the time, according to clinical literature. Lineus Medical is the developer of SafeBreak, a break away medical device that fits in any IV line and prevents IV dislodgement by separating into two pieces. When the device separates, valves on both sides of the device stop the flow of fluids and cause the IV pump to alarm. SafeBreak can be easily and quickly replaced, the IV restarted, and without re-sticking the patient.

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NeoCardial Technologies (Minneapolis, MN) is developing a gentle, minimally invasive cardiac assist device the “eHeart” system, an evolution in mechanical Congestive Heart Failure treatment. Treating patients presently disqualified from existing Ventricular Assist Devices (VADs) due to a myriad of co-morbidities. Research has shown us that the heart is a wrap, a large muscle twisted on itself, forming the right and left ventricles. The eHeart is a compression wrap that gently squeezes the heart, assisting its partially depleted output back to near normal.

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Noleus Technologies, Inc. (Houston, TX) is a medical device, used during and after abdominal surgery to reduce post-operative ileus which is a significant cause of post-operative morbidity and a problem without a good solution. The device accelerates return of bowel function after abdominal surgery, allowing patients to eat and be discharged sooner from the hospital, and have improved outcomes while saving hospitals money, surgeons time and providing a better patient experience.


Nutrimedy (Brookline, MA) is a HIPAA compliant web and mobile platform that connects users to Registered Dietitians for expert nutrition support at their fingertips. We provide more meaningful, longitudinal support through built-in video appointments, secure messaging, file sharing, educational content, customizable trackers, and photo food logging. Nutrimedy can work with medical device companies to deliver nutrition support to patients who receive their devices. In this arrangement, a specific device may be related to a condition in which nutrition plays an important role.


nView Medical, Inc. (Salt Lake City, UT) 3D imaging in surgery using AI image creation algorithms that merge prior information with real-time data gathered during surgery to reduce imaging time and to minimize x-ray radiation.

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RxFunction (Minnetonka, MN) is a neuromodulation medical device start-up that has developed Walkasins, a patented wearable neuroprosthesis for patients with peripheral neuropathy with balance issues. It successfully raised $7.5 million in 2018 and is now looking to raise an additional round to expand commercially. The company is registered and listed Walkasins as a 510k Class II (Exempt) medical device with the FDA. It is commercially released in the U.S. and is executing a second significant clinical study and collecting impressive long-term results.


SentiAR (St. Louis, MO) is developing the first application of Mixed Reality technology for use during cardiac ablation procedures, including the treatment of atrial fibrillation. The SentiAR platform provides an immersive command-center for the clinicians by presenting a 3D hologram of the patient’s electroanatomic data via the Microsoft HoloLens in real-time. Our solution gives the clinician unprecedented control via SentiAR’s patent protected, intuitive gaze interface and provides invaluable insight to guide physician diagnosis and catheter placement.

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Stelect (Melbourne, Australia) is an Australian based medical device company developing a novel coronary imaging balloon catheter. The imaging capabilities provides an inside-out view of the artery, allowing for accurate blockage dimensioning and characterisation. By integrating with a balloon catheter, Stelect minimises the disruption to current procedural workflow and allows for greater reimbursement. The novelty of the Stelect device lies within Stelect’s sensors themselves, the smallest commercially available sensors for intravascular imaging and our ability to integrate these sensors onto existing catheters.

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SubioMed™ (Bloomington, MN) is a pioneer in the invention, development, manufacture, licensing and distribution of Suspension Biomechanics™ technologies associated with gait and balance for providers, patients, and consumers. Biomechanics is the study of the mechanics of the living body, especially of the forces exerted by muscles and gravity on the skeletal structure. SubioMed was created with one simple goal in mind: improve the quality of life for millions of people throughout the world suffering from pain associated with a suboptimal foot + ankle biomechanics.

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Through The Cords (Salt Lake City, UT)is focused on making the challenges associated with difficult airways a thing of the past. Their Total Control Introducer is designed to allow practitioners to finally take full advantage of the superior view provided by video laryngoscopes and provides precise tip control to make the most difficult airways, easy.

Transmural Systems (Andover, MA), established in 2013, stands as a private clinical stage medical device company located in Andover, Massachusetts. The Company has a platform of percutaneous structural heart therapies bringing years of combined implant medical device design, development, quality systems, manufacturing and commercialization experience. The Transmural Systems team successfully advanced two of its products (Cerclage Mitral Annuloplasty and Transcaval Closure Device) from early-stage concept to FDA investigational device exemption (IDE) approval, and is successfully executing early feasibility studies.

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Wise SRL (Milan, Italy) is developing a genuinely new generation of Neuromonitoring and Neuromodulation electrodes by means of its proprietary SCBI technology. WISE’s electrodes are highly ergonomic, conformable, soft and thin, thus allowing great adhesion, minimal invasiveness and excellent adaptability on neural tissues. Currently, WISE is clinically validating its WCS electrodes for electrophysiological brain monitoring and completing the development of the WISE ExPert lead, the first multi-column SCS paddle lead that can be implanted percutaneously by a pain therapist.

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Zepto Life Technology (St. Paul, MN) is building an immunoassay and molecular POC platform with Lab-On-A-Chip technology that boasts high-sensitivity and high-specificity, providing the most accurate and timely clinical diagnostic testing at the point of need.