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AMB Surgical II, LLC (Franklin, OH) AMB Surgical II’s groundbreaking, patented technology is intended to reduce the necessity for invasive and repetitive surgery in children and teens with orthopedic deformities such as scoliosis and limb abnormalities. FLYTE Smart Automated Growing Rod is a sophisticated electro-mechanical, software activated device to provide real-time bio-mechanical feedback to guide treatment, as well as, allow surgeons to perform accurate, non-surgical skeletal adjustments. Through our work, AMB Surgical is advancing the boundaries of modern medicinal practices to participate in a $1B addressable market.

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Ativa Medical (St. Paul, MN) is developing an AI-based bench-top blood and urine testing platform to improve the diagnostics process in primary care settings leading to better treatment decisions and outcomes. We have developed a next-generation micro-fluidics platform (Micro-LAB) that enables nurses and others to perform all the major diagnostic blood and urine test panels immediately onsite, with an artificial intelligence engine that first anticipates which test a doctor will need, and then, with advanced interpretation capability, enhances the value from each test by providing differential diagnosis decision assistance.


Body Vision Medical (Ramat HaSharon, Israel) offers an innovative LungVision(TM) platform, that transforms peripheral lung biopsy into accurate and affordable option, providing substantial clinical benefits. We make any pulmonary lesion visible and accessible through natural opening of the body. Our solution is powered by image fusion and artificial intelligence technologies to address unmet clinical need for early-stage lung cancer diagnostics and treatment. 

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Camras Vision Inc. (Research Triangle Park, NC) has developed the Camras Shunt, a patented device that provides personalized pressure control to attain the highest level of efficacy in stopping the progression of glaucoma. The Camras Shunt is the only glaucoma implant capable of setting eye pressure below 10mm/Hg. We have mitigated investor risk by following a 510(k) pathway to market approval in the US and raising over $3M in non-dilutive financing. The first-in-human trial (12 month follow up) is providing encouraging results. Additional OUS clinical studies will be initiated in 2019.

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CairnSurgical, Inc. (Lebanon, NH) is developing the Breast Cancer Locator (BCL) system for use in Breast Conserving Surgery (BCS) procedures, also known as lumpectomy procedures. Their solution is comprised of a patient-specific device and proprietary software that is used to analyze patient MRI images and provide device manufacturing instructions. The BCL system enables the surgeon with information and a device that provides guidance cues on and within the breast at the start of the procedure to precisely localize, navigate, and resect non-palpable and palpable tumors.

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CellAegis Devices Inc. (CDI) (Mississauga, ON) is a Toronto-based designer and manufacturer of safe, non-invasive and cost effective, cardio protective medical devices. CellAegis Devices has developed and commercialized the non-invasive system, the autoRIC®System, which automates delivery of Remote Ischemic Conditioning (RIC) therapy. The autoRIC® is adjunct to standard of care, has the CE Mark and Health Canada Approval. CellAegis Devices is currently commercializing in Europe and Canada, and conducting registration trials in the USA.

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Conavi Medical Inc. (Toronto, Canada) is a commercial-stage medical device company based in Toronto, Canada that develops image guidance technologies for use in minimally invasive cardiovascular procedures. WATCH an exclusive interview with CEO Dr. Brian Courtney HERE.


CorInnova, Inc. (Houston, TX) With a lead investment from Wellcome Trust, CorInnova is developing a minimally invasive, soft robotic cardiac device in order to create a new paradigm for heart failure treatment.  The device is intended to treat the large number of patients who are contra-indicated for the state-of-the-art left ventricular assist devices (LVADs), thereby reaching three to four times as many eligible patients. The device may also reverse the progression of heart failure or even prevent its development in post-heart attack patients. 


Corvida Medical (Coralville, IA) has developed a device to improve safety of preparing and administering chemotherapy is comprised of a patented line of disposable medical devices that attach to standard vials, syringes, and IV sets to prevent spills, vapor leaks, and needle-sticks. The device is used during the drug preparation phase in the pharmacy compounding area as well as at the bedside during drug delivery.

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Embody LLC (Norfold, VA) is a medical device company developing collagen-based implants for the treatment of tendon and ligament injuries. With $12 million in funding from DARPA, Embody will launch our Tapestry Achilles implant in 2019 following FDA 510(k) clearance. In 2020, we will launch the first collagen internal brace and a Tapestry Rotator Cuff Implant. We have over $6 million in guaranteed, non-dilutive funding going forward, so our investors are funding commercial launch and revenue generation.

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ExplORer Surgical (Chicago, IL) is a digital playbook for surgery and interventional procedures. Our workflows are role-specific and step-specific. Our software is hardware-agnostic, as it can run on any web-enabled device either pre-operatively or live in the OR. We build custom content per custom, with variations available by surgeon as needed. During use, granular intraoperative data is collected. For a hospital, we are able to make preoperative setup more accurate and efficient, provide intraoperative support, and save money on wasted supplies and time. For a device company, we facilitate training & education, as well as provide product support and a sales enablement tool.

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HeartSciences (Westlake, TX) has developed next generation ECG technology through the application of wavelet signal processing and AI. Signal processing is used across many different industries as an important tool to provide insights and new valuable data related to spectral analysis of a signal. HeartSciences’ MyoVista wavECG is a 12-lead resting electrocardiograph utilizing continuous wavelet transform (CWT) based signal processing. Patented informatics detect cardiac dysfunction in the diastolic phase which is associated with all forms of heart disease.


Helius Medical Technologies’ (Newtown, PA) Portable Neuromodulation Stimulator (PoNS®) Treatment is the first and only tongue-delivered neuromodulation that combines stimulation of cranial nerves with physical and cognitive therapy to restore lost neurological function. PoNS Treatment utilizes the Company’s first product in development, known as the portable neuromodulation stimulator or PoNS®; an investigational, non-invasive, medical device.

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IGI Technologies, Inc. (Dayton, MD) IGI Technologies has created a multimodality fusion solution to accelerate interventional radiology (IR) procedures such as biopsies and ablations, reducing time and cost of procedures. Their product, IGT Fusion, is an IR fusion system exclusively focused on revealing non-contrast CT-invisible tumors.

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Inscope Medical Solutions (Jeffersonville, IN) has developed a portfolio of innovative laryngoscopes (direct and video) that optimize intubation, improving this high-risk procedure's efficiency, speed, and safety -- saving lives and lowering costs for healthcare providers.

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LightIntegra Technology Inc. (Vancouver, BC) Failed platelet transfusions are a major issue in healthcare, impacting the care of blood cancer patients, and wasting $1.6 billion annually in the US. LightIntegra knows how painful failed transfusions are for physicians, the blood bank, and most importantly, the patients. Understanding this struggle is what gave birth to ThromboLUX, the first analyzer to provide a routine test for platelet activation status. LightIntegra strives to give patients the best possible chance for platelet transfusion success by ensuring all hematology-oncology patients receive non-activated platelets.

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Marblehead Medical LLC (Maple Grove, MN) is developing the Next Generation of Stroke Treatment Technology. We will replace the Balloon Guide Catheter with Marblehead’s Balloon Guide Sheath. A combination product that we call Balloon Occlusion Sheath for Stroke (BOSS). Solves ALL current balloon guide catheter problems: Smaller arterial access → fewer complications; Larger inner diameter → better suction, fits all clot-grabbers; Improved support → doesn’t “fall over” in aorta; Fewer steps → shorter procedure time; Innovative balloon shapes → fewer clots breaking up and causing distal strokes.

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Medicem (Kladno, Czech Republic) is developing a cutting edge intraocular lens (IOL) and laser system that can adjust the IOL non-invasively in-situ using a femtosecond laser. The femtosecond laser adjustable lens (FSLA-IOL) aims to increase significantly the predictability of the lens replacement surgery and become enabling technology for accelerated premium IOL market growth. Addressable market is represented by about 26 million cataract surgeries per year globally and several hundred million presbyopia patients using reading glasses instead of surgery today.

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NanoVault Medical, LLC (St. Paul, MN) has utilized nanotechnology to sculpt porous membranes with pore diameters of 10s of nanometers (nm). These nanopores provide a protective barrier for transplanted cells and tissues, isolating them from immune system attack. NanoVault engineeres this nanoscale material feature into a highly biocompatible metallic, capsule-like architecture to solve many of the challenges of cellular and biotherapeutic encapsulation and immunoisolation. This includes insulin-producing, stem cell-derived Beta cells as an alternative to exogenous insulin, a $43 billion global market.

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NightWare (Minneapolis, MN) is a digital therapeutics company treating Nightmare Disorder resulting from PTSD. NightWare is software that runs on the Apple Watch, and after a learning period, detects a nightmare and intervenes to arouse the sleeper out of the nightmare without waking them. NightWare has had excellent preliminary results and is currently conducting our pivotal RCT with the Minneapolis VA . NightWare projects FDA clearance and product launch in 2020.

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Ōmcare, LLC (Burnsville, MN) is a health technology company. We deliver remote care and real medication adherence. We do this by extending the reach of the caregiver thru our proprietary interactive IoT technologies - promising right pill, right time, right person. By partnering with pharmacies, payers, providers and family caregivers we help people live healthier, more vibrant, independent lives. If independence is freedom, then Ōmcare is liberating the essence of life and empowering independence in more ways than one each and every day. Ōmcare. Be there from anywhere.

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Prima-Temp (Boulder, CO) Prima-Temp technology utilizes circadian rhythm patterns known as chronobiology to track a variety of important health parameters including ovulation prediction, sleep and weight metabolism, cancer chemotherapy timing, infection and sepsis identification. All leading to potential successful treatment and outcomes. Chronobiology is the Nobel Prize winning concept that has the ability to identify and potentially solve many of today’s health issues. Focusing first on women’s reproductive health, Priya, our first product, will alert women to their “fertile window” as they move toward conception.

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RxFunction (Minnetonka, MN) is a start-up medical device company focused on designing and bringing to market medical technologies that restore balance, increase mobility, and enhance confidence. Our first product is Walkasins, a one-of-a-kind, non-invasive sensory neuroprosthesis that improves balance for people with sensory peripheral neuropathy at risk of falling. RxFunction is privately held and headquartered in Eden Prairie. Walkasins is manufactured in Minnesota, has not been submitted to the FDA for review, and is not yet available for sale in the U.S.

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Sense Diagnostics, Inc. (Cincinnati, OH) When a patient’s brain is injured, time is everything. The SENSE scanner is a low power “radar for the brain” that uses radio waves to detect stroke and TBI in minutes. It will improve triage patients - getting patients to the right hospital and getting treatment started sooner. In the hospital, the scanner rapidly detects brain injuries that get worse – before significant brain damage is done. SENSE will minimize treatment delays, helping save lives, avoid disability and lower treatment costs.

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Synergy Disc Replacement (Boulder, CO) is the first and only Total Disc Replacement implant that unifies the needs for sagittal balance and motion into an alignment correcting cervical disc. Proprietary alignment features allow it to be used in patients that do not have a normal alignment. This unique ability makes Synergy-Disc the only viable alternative to fusion in patients with pre-operative alignment problems.

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TAS Medical (San Carlos, CA) – TAS Medical's Trans Abdominal Strap will meet the large unmet need to close ventral hernia defects laparoscopically while providing millions of dollars in savings for healthcare.

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UroCure, LLC (Minneapolis, MN) Re-commercialize slings for female incontinence with IP re-acquired from AMS. We will design, develop and commercialize the products and re-submit for FDA clearance according to previously established 510(k) pathway. Slings are gold standard and are reimbursed in all geographies. During product development phase, the company will use an experienced team of contractors with in-depth knowledge of space, sling design/manufacturing and physicians.

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Vallum Corporation (Nashua, NH) - More than one-hundred million dollars has been expended in developing our proprietary Accelerated Neutral Atom Beam processing technology (ANAB). ANAB processing makes interbody fusion devices (IBDs) hydrophilic by superimposing a nanotexture (20-50nm) onto the surface microtopography of virgin PEEK. The nanotexturing created by ANAB processing is well-documented in promoting osteoblast functions. In a recent GLP ovine study, Vallum’s ANAB-treated PEEKplus IBDs demonstrated superior bone bridging and superior quality of new bone formation at four-months compared to untreated PEEK IBD controls, titanium coated IBDs and HA infused IBDS.

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Virtuoso Surgical, Inc. (Nashville, TN) The Virtuoso device uses nitinol concentric-tube technology to control multiple surgical arms and tools through a 5-8 mm rigid endoscope. The device is based on technology developed at Johns Hopkins University and Vanderbilt University by Virtuoso's President, Dr. Robert Webster, and others. The Virtuoso device is expected to be used in a myriad of endoscopic applications, including benign prostatic hyperplasia (BPH), central-airway obstructions, colloid-cyst removal in the brain, gynecologic surgeries, and other endoscopic applications. To date, the Company has been primarily funded through government grants (SBIR, STTR, and a State SBIR matching grant) and private seed capital. It is currently raising Series A funding through a preferred-share issuance.


Xact Medical LLC (Springboro, OH) - A critical unmet need for fast and reliable central vascular access has created a new paradigm in medical robotics – Fast Intelligent Needle Delivery (FIND). FIND is a robotic ultrasound transducer that is small, fast, and easy to use. It automates ultrasound guided needle placement, enabling every clinician to precisely place needles like an expert. FIND is suitable for any application requiring precision needle placement, creating an addressable market of over $3B, with an intended beachhead market of central vascular access.