The SteriPlas Cold Plasma medical device by Adtec Healthcare Ltd (Twickenham, London UK) is a strong antibacterial with proven clinical efficacy for the management of chronic wounds, LVAD driveline infections, diabetic foot ulcers and deep sternal wound infections typically complicated with biofilm. Where conventional therapies, such as antibiotics, fail to destroy bacteria protected within biofilm leading to a worsening infection, the SteriPlas delivers a quick, painless and fast-acting solution to physically destroy all forms of bacteria regardless of their resistance profile.

Therapeutic: Wound Management; Infection control

Vita AV by AVeta Medical (Galway, Ireland) is a non hormonal therapeutic medical device for the treatment of Vaginal Atrophy.

Therapeutic: Women’s Health; Menopause / GSM/ Vaginal Atrophy

RoboticScope, a revolutionary surgical microscope crafted by BHS Technologies (Innsbruck, Austria), integrates a head-mounted display, a 3D camera mounted onto a 6-axis robotic arm, and advanced computing capabilities, redefining the landscape of surgical microscopes. BHS Technologies is a full-scale organization with over 40 employees, holding ISO 13485 certification and FDA listing. The device has obtained CE marking and FDA approval, has been commercially available since the mid-2020. More than 3,000 surgeries have been performed, with many more to come.

Therapeutic: Minimally Invasive Surgery

Colospan (Israel) introduces a novel device for colorectal surgery that aims to prevent the profound clinical and economic consequences associated with anastomotic leaks and diverting stomas, a $5B market opportunity. The company's lead product is a single-use, temporary intraluminal bypass device designed to protect the anastomotic site. With over 110 patients treated in clinical studies with excellent results and compelling surgeon feedback, Colospan has successfully received CE mark (MDR) and FDA IDE approval to launch a US pivotal study.

Therapeutic: Surgery; Colorectal

Alexandre Chau

CEO

endomina by Endo Tools Therapeutics (Charleroi, Belgium) is a commercially available suturing platform targeting endoscopic gastroplasty (for bariatric/metabolic surgery), reflux treatment and GI tumor resection. It has been succesfully used in more than 1000 procedures (mostly gastroplasty). It is cleared in the US and CE marked in Europe. This funding round aims at expanding clinical indications in the US and ramp up commercial activities.

Therapeutic: Gastroenterology; Obesity

Boris Schmitt

CEO

GrOwnValve GmbH (Berlin, Germany) revolutionizes heart valve replacement with a groundbreaking autologous procedure. Our technology enables the creation of personalized, growing heart valves from the patient's own tissue, using a unique catheter-based approach. Designed for a single operation, it promises a swift recovery, no visible scarring, and eliminates the need for lifelong medication. Focused on improving patient outcomes and quality of life, GrOwnValve represents a significant advancement in treating congenital and acquired heart valve diseases.

Therapeutic: Cardiovascular; Structural heart

Leo Smit

CEO

Revolutionizing cartilage recovery: Hy2Care’s (Geleen, Limburg, the Netherlands) CartRevive™ hydrogel implant realizes optimal regeneration of cartilage defects. After sports mishaps, slips, or falls, our patented hydrogel offers a scaffold of joint-matching composition, guiding natural cell growth and enabling the body to heal itself. Currently under clinical examination in the Netherlands for EU approval, with US trials coming up. Dive into the future of joint repair with us!

Therapeutic: Orthopedics-Spine; Regenerative Medicine

Marco Pisano

CEO

Lymphatica Medtech (Lausanne, Vaud, Switzerland) has developed, and clinically demonstrated in a positive FIH study, LymphoDrain: a revolutionary device for the treatment of lymphedema, a chronic condition with no cure affecting over 10 million patients in US and Europe.

Therapeutic: Cardiovascular

Orixha’s (Maisons-Alfort, France) mission is to develop Liquid Ventilation Medical Devices to save lives in Critical Care. Orixha develops Vent2Cool based on its proprietary Lung Conservative Liquid Ventilation to shield the critical organs (brain, heart) from reperfusion injury.  Vent2Cool improves survival and morbidity outcomes of Post Cardiac Arrest Syndrome by transforming the lungs into an efficient heat exchanger with the circulating blood to induce ultra-rapid therapeutic hypothermia – reaching the 33°C protective temperature within minutes vs. hours with current hypothermia devices. Orixha’s proprietary total liquid ventilation technology platform, once validated in therapeutic hypothermia, will be developed for other Critical Care conditions such as Acute Respiratory Distress Syndrome.

Therapeutic: Medical device / Intensive Care / Critical Care / Respiratory support

Phosphoenix (Amsterdam (North Holland), The Netherlands) is a Dutch MedTech start-up with a mission to restore lost vision through an innovative neuroprosthesis that bypasses the eyes and directly interfaces with the brain. Distinguished by its high resolution, expansive visual field coverage, and long-term durability, our revolutionary approach leverages existing technologies and established neurosurgical practices. Beyond vision restoration, our neuroprosthesis technology will enable other brain-based therapies, ranging from motor movement restoration to neuromodulation therapy.

Therapeutic: Neuromodulation-Neurostimulation

Adriaan Hart de Ruijter

Chairman of the Board

Preventicus (Jena, Thüringen, Germany) provides managed care programs and technology for cardiovascular disease through early detection, diagnosis and monitoring. Innovative telecare technology, clinical evidence and proven health-economic outcomes, in compliance with medical guidelines, offer value to patients and health insurances.

Therapeutic: Cardiovascular, Stroke

Cynthia Chen

Chairlady and Executive Vice President

Pulnovo Medical (Shanghai, China) has developed, patented, registered the global first-in-class Pulmonary Artery Denervation (PADN®) therapeutic device to enhance the medical prognosis and improve quality of life for pulmonary hypertension and heart failure patients. For over a decade, Pulnovo has a leading position in PADN's therapeutic mechanism of action exploration, clinical data establishment, product development and commercialization.

Therapeutic: Cardiovascular; Interventional procedure

Franz Bozsak

CEO and co-founder

Sensome (Massy, France) is a clinical-stage start-up revolutionizing healthcare with its patented sensor technology. By combining the world's smallest impedance-based microsensors and machine learning, Sensome's technology identifies biological tissues in real-time, transforming invasive medical devices into connected healthcare devices. The first product, the Clotild® Smart Guidewire System, is undergoing clinical trials and has the potential to improve stroke treatment. Sensome's technology has applications beyond stroke, including peripheral vascular intervention and interventional oncology.

Therapeutic: Neurovascular

Berk Tas

CEO

SentiAR’s (St Louis, MO) CommandEP system is world’s first and only FDA Approved holographic cardiac ablation guidance system. The system creates a holographic, patient specific digital twin in real time and provides physicians the ability to manipulate their views through a hands-free interface. Clinical studies have shown system can improve physician navigation accuracy as well as communication load in the room.

Therapeutic: Augmented Reality

Visa Sippola

CEO

In many fields of surgery, bone-cutting procedures involve the risk of complications caused by the surgical drill damaging vital soft tissues such as blood vessels or central nervous system structures. Such complications can severely affect patients' quality of life and result in significant costs. Surgify Halo by Surgify Medical (Espoo, Finland) is a tissue-selective bone-cutting technology that offers improved safety, precision, and speed during neurosurgical and orthopedic procedures. The novel product provides high accuracy and a unique soft-tissue protection shield for less-invasive surgery. The improved safety is delivered through Surgify Halo's patented safety mechanism, a tissue-selective safety shield around the burr, which activates automatically when the drill bit encounters tissue softer than bone during surgery. On the other hand, the cutting mode is activated when placed on bone or other hard tissue.

Therapeutic: Surgery

Our mission at SymPhysis Medical (Dublin rd., Galway, Connaught, Ireland) is to enhance the palliative care pathway to provide unrivalled patient independence and reduce hospitalisations for people with life-limiting cancers. releaze is our emergent technology to treat fluid build-up in the chest cavity caused by cancer. releaze is a user-centric drainage catheter system that allows patients to drain at home fully independently and incorporates an active patent-pending mechanism to accelerate time to catheter removal compared to current systems.

Therapeutic: Oncology/Palliative Care / Malignant Pleural Effusion